Formerly known as causalgia or reflex sympathetic dystrophy (RSD), complex regional pain syndrome (CRPS) is a chronic pain condition marked by intense, ongoing pain that is disproportionate to the severity of the initial injury. CRPS usually affects one limb, following trauma or injury, but the pain is more intense and persistent than one would anticipate. A complex regional pain syndrome specialist can provide targeted treatment and pain management strategies to help alleviate the symptoms and improve quality of life.

It is thought that CRPS results from an aberrant reaction of the central and peripheral nerve systems to damage. Though the exact origin is unknown, a combination of vascular, neurological, and inflammatory mechanisms are considered to be involved.

Pain experts, neurologists, physiotherapists, and psychologists are often part of a multidisciplinary team that manages CRPS in India. A mixture of physical therapy, nerve blocks, psychological support, and drugs (such as painkillers, anti-inflammatories, and antidepressants) may be used throughout treatment.

Advanced therapies like spinal cord stimulation and intrathecal drug delivery devices are among the therapeutic options for complex regional pain syndrome (CRPS) that healthcare facilities in India provide. Access to these treatments, however, can differ according on the area and medical facility.

Causes Of Complex Regional Pain Syndrome (CRPS)

Complex Regional Pain Syndrome (CRPS) can develop following a heart attack, stroke, surgery, or accident. Although the precise origin of CRPS is unknown, it is thought to be related to complicated interactions between the immune system, inflammation, and central and peripheral nerve systems. The following are a few possible reasons and elements that could lead to the onset of CRPS:

Trauma or Injury
A fracture, sprain, or surgical procedure are common cause of chronic regional pain syndrome (CRPS). However, there's not always a direct correlation between the severity of the injury and the intensity of CRPS symptoms.
Peripheral Nerve Dysfunction
Peripheral nerve dysfunction in CRPS patients may result in aberrant pain signals. Hypersensitivity of the nerves can result in pain even from small stimulation.
Inflammatory Response
Research indicates that CRPS may be associated with an inflammatory response, as seen by elevated inflammatory marker levels in the affected limb.
Variations in Blood Flow
CRPS may cause variations in the limb's blood flow and circulation, which may cause temperature and skin tone alterations.
Central Sensitization
CRPS may be associated with modifications to the central nervous system, which can result in altered pain perception and greater pain sensitivity.
Hereditary Considerations
Additional research is needed to determine whether any hereditary characteristics predispose people to getting CRPS.

Symptoms of Complex Regional Pain Syndrome (CRPS)

Severe and Persistent Pain
CRPS typically presents with intense, continuous burning, throbbing, or shooting pain, often disproportionate to the initial injury.
Sensitivity to Touch
Affected limbs may exhibit heightened sensitivity to touch, causing discomfort even with gentle contact.
Temperature and Texture Alterations
Skin on the affected limb may display temperature variations, appearing hotter or colder than surrounding areas. Texture changes such as thinning, glossiness, or excessive sweating may also occur.
Swelling and Stiffness
Swelling and stiffness in the affected limb can hinder normal movement and usage.
Skin Tone Changes
The skin may exhibit changes in tone, appearing pale, blotchy, or mottled.
Coordination and Muscle Weakness
Weakness, loss of coordination, and restricted joint mobility may affect the afflicted limb, impairing daily activities.

Treatment of Complex Regional Pain Syndrome (CRPS)

Physical Therapy:
Physical therapy plays a pivotal role in complex regional pain syndrome management, focusing on reducing pain, swelling, and enhancing coordination, strength, and mobility. Techniques such as stretching, desensitization exercises, and gentle exercise are utilized.
Pharmacotherapy:
Various medications, including prescription antidepressants, anticonvulsants, and opioid analgesics, along with over-the-counter pain relievers like acetaminophen or ibuprofen, are employed to alleviate CRPS symptoms. Topical pain relief options like lidocaine patches are also utilized.
Sympathetic Nerve Blocks:
Anaesthetic injections into the spinal area are administered to disrupt the sympathetic nerves responsible for CRPS symptoms, aiding in both diagnosis and pain relief.
Spinal Cord Stimulation (SCS):
SCS involves implanting a device near the spine to deliver electrical impulses to nerves, potentially reducing pain perception, particularly in severe, refractory CRPS cases.
Intrathecal Drug Delivery:
A catheter and pump system deliver medications directly into the spinal fluid, offering targeted pain relief for individuals with severe, unresponsive CRPS.
Psychological Support:
Psychological interventions such as cognitive-behavioural therapy (CBT), counselling, and support groups are invaluable in managing the emotional impact of CRPS and coping with chronic pain.

CRPS treatment is individualized, often incorporating a multidisciplinary approach involving pain specialists, neurologists, physical therapists, and psychologists to optimize outcomes and address the complex nature of the condition.

Do's for CRPS

  • Remain active. Physical treatment and little exercise can help keep the affected limb mobile, less stiff, and have better circulation. Create a safe and efficient workout program in collaboration with a healthcare provider.
  • Take good care of yourself by eating a balanced diet, getting plenty of sleep, and drinking lots of water to maintain your general health and well-being.
  • Control your stress. Stress exacerbates CRPS symptoms such as discomfort. To assist manage stress, engage in stress-reduction practices like deep breathing, meditation, or yoga.
  • Use assistive devices to help you carry out daily duties more comfortably and lessen the strain on the affected limb, think about utilizing assistive devices like braces, splints, or adapting tools..
  • Keep yourself updated. Learn about the treatment and management of CRPS. You can make more educated decisions regarding your care if you are aware of your condition.
  • Seek assistance. Making new friends or joining a support group can help you get important emotional support as well as useful advice on how to manage your CRPS.
  • Observe your course of treatment. Follow the prescription drugs, physical therapy, and other interventions outlined in the treatment plan that has been prescribed by your medical team. Effective complex regional pain syndrome management requires consistency.

Don'ts for CRPS

  • Steer clear of extended inactivity. Although rest is necessary, extended inactivity can cause stiffness and weakening of the muscles. As much as you can, within reason, continue to be active.
  • Don’t disregard symptom changes. Keep an eye out for any changes in your symptoms and let your medical team know about them. The condition can be kept from getting worse with early intervention.
  • Refrain from overusing the affected limb. Maintaining an active lifestyle is crucial, but overusing the affected limb can exacerbate discomfort and inflammation.
  • Never self-medicate. Refrain from changing your treatment plan or taking medication on your own without first speaking with your doctor. Certain drugs may interact with other medications or cause negative effects.
  • Steer clear of extremes in temperature. CRPS symptoms may intensify in situations that are extremely hot or cold. Take care to shield the afflicted limb from extremely hot or cold conditions.
  • Never lose hope. Although managing symptoms and leading a fulfilling life can be difficult for many people with CRPS, with the correct support and therapy, this is achievable for many.

Dr. Anushka Patel - Complex Regional Pain Syndrome Specialist

There are several benefits to consulting with a pain management specialist. It is typical to concentrate on the affected area when a patient is in pain. Still, it’s also critical to understand the patient’s medical history, way of life, and eating and sleeping habits, in addition to the symptoms and underlying causes. Because of her training and experience, Dr. Anushka can determine the underlying source of the problem. With a correct diagnosis, she has a good prognosis for you to look forward to. Dr. Anushka is a highly sought-after pain management specialist because she places a high importance on the care provided during and after surgery or therapy.